Rabeprazole Sodium Pellets

Rabeprazole Sodium Pellets Specification

Purity
99% Min.

Taste
Bitter

Molecular Weight
381.42 g/mol

Properties
Gastric acid secretion inhibitor, stability in enteric coating conditions

Melting Point
136-140C

Usage
Treatment of gastroesophageal reflux disease, duodenal ulcers and related disorders

Molecular Formula
C18H20N3NaO3S

HS Code
29420090

Appearance
White to off-white pellets

Poisonous
NO

Ingredients
Rabeprazole Sodium, Excipients

Smell
Odorless

Grade
Pharmaceutical Grade

Product Type
Active Pharmaceutical Ingredient (API)

Application
Used as proton pump inhibitor in pharmaceutical formulations

Shelf Life
36 Months

Solubility
Freely soluble in methanol, practically insoluble in water

Storage
Store in a cool, dry place, protected from moisture

Shape
Spherical Pellets

CAS No
117976-90-6

Physical Form
Pellets

Structural Formula
Available on request

Loss on Drying
Not more than 5%

Packaging
Double LDPE bags placed in a HDPE drum

Microbial Limit
Complies as per pharmacopoeial standards

Identification
Complies with standard tests for Rabeprazole Sodium

Particle Size
90% between 0.2 mm to 1.18 mm

Heavy Metals
Not more than 20 ppm

Assay (Rabeprazole Sodium)
Not less than 99.0% and not more than 101.0%

About Rabeprazole Sodium Pellets

Rabeprazole sodium pellets are a pharmaceutical formulation of the proton pump inhibitor (PPI) drug, rabeprazole sodium. The pellets consist of small, spherical particles containing the active ingredient, which is used to treat acid-related disorders such as gastroesophageal reflux disease (GERD) and peptic ulcer disease.

Rabeprazole sodium works by blocking the proton pumps in the stomach lining, which are responsible for producing acid. By reducing the amount of acid in the stomach, rabeprazole sodium can alleviate symptoms such as heartburn, regurgitation, and stomach pain.

The pellets are usually encapsulated in a capsule or a tablet to facilitate ingestion. The pellets are designed to release the drug gradually, which allows for sustained blood levels and prolonged therapeutic effect.

Rabeprazole sodium pellets are available in different strengths and formulations, and their use should be prescribed by a healthcare provider based on the patient's medical condition, age, and other factors. As with all medications, rabeprazole sodium may cause side effects such as headache, nausea, diarrhea, and stomach pain, and patients should consult their healthcare provider if they experience any adverse effects.

Superior Pharmaceutical Grade Quality

Rabeprazole Sodium Pellets are produced to meet strict pharmaceutical standards, ensuring high purity, consistent particle size, and compliance with all necessary identification, microbial, and heavy metal limits. Their stable formulation makes them highly suitable for enteric coating applications in tablet or capsule manufacturing.

Optimal Packaging and Storage

These pellets are packaged securely in double LDPE bags placed within HDPE drums to prevent contamination and moisture ingress. For best preservation, they should be stored in cool, dry environments away from direct exposure to humidity and heat, maintaining efficacy for up to 36 months.

Clinical Applications and Benefits

Rabeprazole Sodium Pellets are beneficial as proton pump inhibitors, effectively treating conditions like gastroesophageal reflux disease (GERD), duodenal ulcers, and related gastric disorders. Their targeted pharmacological action provides rapid and sustained relief from excessive gastric acid production.

FAQs of Rabeprazole Sodium Pellets:

Q: How are Rabeprazole Sodium Pellets typically used in pharmaceutical formulations?

A: Rabeprazole Sodium Pellets are incorporated into enteric-coated tablets or capsules, allowing for controlled release in the gastrointestinal tract, primarily for treating GERD and peptic ulcer conditions.

Q: What quality standards do Rabeprazole Sodium Pellets comply with?

A: These pellets comply with pharmacopoeial standards for identification, microbial limits, heavy metals (not more than 20 ppm), and loss on drying, ensuring product safety and efficacy.

Q: When should Rabeprazole Sodium Pellets be prescribed or used?

A: They are recommended for patients experiencing symptoms of chronic heartburn, acid reflux, duodenal ulcers, or similar gastrointestinal disorders, as directed by healthcare professionals.

Q: Where are Rabeprazole Sodium Pellets manufactured and exported from?

A: Rabeprazole Sodium Pellets are produced and supplied from India, catering to domestic and international pharmaceutical markets as an exporter, importer, and supplier.

Q: What is the standard process for packaging Rabeprazole Sodium Pellets?

A: The pellets are packed in double LDPE bags, which are then placed inside HDPE drums to ensure protection from moisture and environmental contaminants during storage and transportation.

Q: What benefits do Rabeprazole Sodium Pellets offer in medical treatment?

A: They provide targeted inhibition of gastric acid secretion, resulting in rapid symptom relief and improved healing rates for gastrointestinal disorders while exhibiting stability in formulation.

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